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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPS8L2 All Species: 13.33
Human Site: S535 Identified Species: 41.9
UniProt: Q9H6S3 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6S3 NP_073609.2 715 80621 S535 W W K L R S R S G Q A G Y V P
Chimpanzee Pan troglodytes XP_512904 745 82543 L567 G Y V P Y N I L T P H P G P R
Rhesus Macaque Macaca mulatta XP_001116697 615 68955 D458 S G W E P P V D V L Q E A P W
Dog Lupus familis XP_534881 791 88639 S543 W W K V R N A S G D S G F V P
Cat Felis silvestris
Mouse Mus musculus Q99K30 729 82211 S538 W W K L R N R S G Q A G Y V P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510664 556 62861 T399 S T Q A P G R T Q S F R S Q P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666818 677 76506 D517 Y V P Y N I L D V I K L E D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785396 970 107261 S770 Q L E V K N T S G Q S G Y V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.2 79.7 42.5 N.A. 84 N.A. N.A. 29 N.A. N.A. 56.5 N.A. N.A. N.A. N.A. 24.6
Protein Similarity: 100 58.2 80.8 60.1 N.A. 90.1 N.A. N.A. 46.1 N.A. N.A. 70.7 N.A. N.A. N.A. N.A. 40.5
P-Site Identity: 100 0 0 60 N.A. 93.3 N.A. N.A. 13.3 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 13.3 0 86.6 N.A. 100 N.A. N.A. 26.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 0 13 0 0 0 25 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 25 0 13 0 0 0 13 0 % D
% Glu: 0 0 13 13 0 0 0 0 0 0 0 13 13 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 13 0 13 0 0 % F
% Gly: 13 13 0 0 0 13 0 0 50 0 0 50 13 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 13 0 0 13 0 0 0 0 0 % I
% Lys: 0 0 38 0 13 0 0 0 0 0 13 0 0 0 0 % K
% Leu: 0 13 0 25 0 0 13 13 0 13 0 13 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 13 50 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 13 13 25 13 0 0 0 13 0 13 0 25 75 % P
% Gln: 13 0 13 0 0 0 0 0 13 38 13 0 0 13 0 % Q
% Arg: 0 0 0 0 38 0 38 0 0 0 0 13 0 0 13 % R
% Ser: 25 0 0 0 0 13 0 50 0 13 25 0 13 0 0 % S
% Thr: 0 13 0 0 0 0 13 13 13 0 0 0 0 0 0 % T
% Val: 0 13 13 25 0 0 13 0 25 0 0 0 0 50 0 % V
% Trp: 38 38 13 0 0 0 0 0 0 0 0 0 0 0 13 % W
% Tyr: 13 13 0 13 13 0 0 0 0 0 0 0 38 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _